P-P24 Optimising post-operative nutrition in patients undergoing pancreaticoduodenectomy

Abstract Background A considerable number of patients undergoing pancreaticoduodenectomy require supplemental nutrition in the postoperative period. However, there remains no national consensus on optimal feeding modality. Furthermore, at our institution a variation practice exists when considering post-operative entera (via naso-jejunal (NJ)) or parenteral (PN). This study aimed to evaluate utility enteral centre and explore risk factors predisposing nutritional deficits requiring supplementation. Methods We retrospectively analysed electronic case records all between November 2019 2020 HPB specialist centre. Key patient demographic data requirements with route, length indication for as well biochemical markers, stay (LoS) complications were collected analysed. Data via intention treat analysis. Results 48 underwent pancreaticoduodenectomy, which 26 had an NJ tube inserted intra-operatively. 16 (33%) required feeding, route 7 PN 9. 2 intolerant feeds progressed PN. fed shorter LoS (12(10-42) vs. 28(14-63) days)(p = 0.09) compared feeding. PN-related line infection thrombosis 4 (36%) patients. Supplemental met daily kcal 13 (81%) patients, but was associated greater weight loss (-5%) than (-3%). Significantly increasing needing nutrition: advanced age(p 0.04), ASA≥2(p 0.04) anastomotic leak(p 0.02). Conclusions In this group largely well-tolerated majority their route. Due increased incidence PN, should be considered 1st option supplementation, intra-operative insertion higher-risk